Comparison of Anterior and Posterior Segment Parameters According to Iris Color Spectrum
Year 2022, Volume: 3 Issue: 2, 168 - 176, 29.12.2022Abstract
AİM: Comparison of eye anterior and posterior segment parameters according to iris color
METHODS: 150 eyes of 150 patients who applied to Aksaray Training and Research Hospital between 2019-2020 were included in the study. 28 blue, 30 green, 29 light brown (light pigmentation), 31 medium brown (medium pigmentation) and 30 dark brown (heavy pigmentation). ) eyes, 5 groups of patients were included in the study. Biomicroscopy and fundus examination were performed on the patients. After measuring the refraction of the patients, corneal topography and optical biometry, Intraocular Pressure (IOP), Central Corneal Thickness (CCT), Anterior Chamber Depth (ACD), Anterior Chamber Angle (ACA), Lens Thickness (LK), Axial Length (AU) Retinal nerve fiber thickness (RSLK), central retinal thickness (CRC) and subfoveal choroidal thickness (SFKK) measurements were made with OCT.
RESULTS: The mean age of the patients was 33.4 ±5.5, 35.7±4.7, and 32.9 ±6.7 in patients with blue, green and brown eyes, respectively. There were 15 women and 13 men in the blue-eyed group, 16 women and 14 men in the green-eyed group, and 47 men and 43 women in the brown-eyed group. In terms of anterior and posterior segment parameters, a difference was found between blue eyes and brown eyes in terms of CCT, ACD and LK (p=0.035, 0.004 and 0.012). A difference was found between blue eyes and green eyes in terms of ACD and LK (p=0.006 and 0.041). There was no significant difference between the anterior and posterior segment parameters of the green-eyed and brown-eyed patients. In addition, there was no difference between the groups in terms of other factors. As a result of the correlation analysis performed in terms of parameters according to iris pigmentation level, no positive or negative correlation was found with any parameter.
CONCLUSİONS:When evaluating patients, it should be kept in mind that the normal values of some eye parameters may vary according to the differences in iris color.
Keywords
iris color spectrum, pigmentation, central corneal thickness, subfoveal choroidal thickness
References
- 1. Liu, F., Wollstein, A., Hysi, P.G., et al. (2010). Digital quantification of human eye color highlights genetic association of three new loci. PLoS Genet, 6, e1000934.
- 2. Grimm, C., Wenzel. A., Williams, T., et al. (2001). Rhodopsin-mediatedblue-light damaget other at retina: effect of photoreversal of bleaching. Invest Ophthalmol Vis Sci, 42, 497–505.
- 3. Hu, D.N., Mccormick, S.A., Orlow. S.J., Rosemblat, S., Lin, A.Y., Wo, K.(1995) Melanogenesis by Human Uveal Melanocytes in-Vitro. Invest Ophtalmol Vis Sci, 36(5), 931-938
- 4. Meng, W., Butterworth, J., Calvas P., et al.(2012). Myopia and iris colour: a possible connection? Med Hypotheses, 78, 778–80.
- 5. Sun, H.P., Lin, Y., Pan, C.W. (2014). Iris color and associated pathological ocular complications: a review of epidemiologic studies. Int J Ophthalmol , 7, 872–8.
- 6. Yahalom, C., Tzur, V., Blumenfeld, A., et al. (2012). Refractive profile in oculocutaneous albinism and its correlation with final visual outcome. Br J Ophthalmol, 96, 537–9.
- 7. White, D., Rabago-Smith, M.(2011). Genotype-phenotype associations and human eye color. J Hum Genet, 56(1), 5–7.
- 8. Younan, C., Mitchell, P., Cumming, R.G., Rochtchina, E., Wang, J.J. (2002). Iris color and incident cataract and cataract surgery: the Blue Mountains Eye Study. Am J Ophthalmol, 134(2), 273–4.
- 9. Di Stasio E, Maggi D, Berardesca E, Marulli GC, Bizzarri C, Lauria A et al.(2011). Blue eyes as a risk factor for type 1 diabetes. Diabetes Metab Res Rev, 27(6),609–13.
- 10. Cumming, R.G., Mitchell, P., Lim, R. (2000) Iris color and cataract: the Blue Mountains Eye Study.Am J Ophtalmol, 130(2), 237-238
- 11. Leske, M.C, Wu, S.Y., Nemesure, B., Hennis, A.(2002). Barbadors Eye Studies Group. Risk factors for incident nuclear opacities. Ophtalmology 109(7), 1303-1308.
- 12. Schmidt-Pokrzywniak, A., Jockel, K.H., Bornfeld, N., Sauerwein, W., Stang, A.(2009). Positive Interaction Between Light Iris Color and Ultraviolet Radiation in Relation to the Risk of Uveal Melanoma A Case-Control Study, 116(2), 340-348.
- 13. Klein, R., Klein, B.E., Jensen, S.C., Cruickshanks, K.J. (1998). The relationship of ocular factors to the incidence and progression of age-related maculopathy. Arch Ophtalmol, 116(4), 506-513 .
- 14. Khan, J.C., Shahid, H., Thurlby, D.A, Bradley, M., Clayton, D.G, Moore, A.T., Bird ,A.C., Yates, J.R. (2006). Genetic Factors in AMD Study. Age related macular degeneration and sun exposure, iris colour, and skin sensitivity to sunlight. Br J Ophtalmol, 90(1), 29-32.
- 15. McCarty, C.A., Mukesh, B.N., Fu, C.L., Mitchell, P., Wang, J.J. (2001). Taylor HR. Risk factors for age-related maculopathy: the Visual Impairment Project. Arch ophtalmol, 119(10),1455-1462
- 16. Jonas, J.B., Budde, W.M., Stroux, A., Oberacher-Velten, I.M. (2006). Iris colour, optic disc dimensions, degree and progression of glaucomatous optic nerve damage, 34(7),654-660
- 17. Saw, S.M. (2003). A synopsis of the prevalence rates and environmental risk factors for myopia.Clin Exp Optom. 86(5),289-294.
- 18. Young, T.L., Metlapally, R., Shay, A.E. (2007). Complex trait genetics of refractive error. Arch Ophtalmol, 125(1), 38-48.
- 19. Vannas, A.E., Ying, G.S., Stone, R.A.,(2003). Maguire MG, Jormanainen V, Tervo T. Myopia and natural lighting extremes: risk factors in Finnish army conscripts, 81(6), 588-595.
- 20. Pan, C.W., Ke, C., Hu, D.N., Li, J., Zhong, H.(2009). Iris colour and astigmatism among Chinese teenagers. Br J Ophthalmol. 103(12), 1810-1814.
İris Renk Spektrumuna Göre Ön ve Arka Segment Parametrelerinin Karşılaştırılması
Year 2022, Volume: 3 Issue: 2, 168 - 176, 29.12.2022Abstract
AMAÇ: İris rengine göre göz anterior ve posterior segment parametrelerinin karşılaştırılması
YÖNTEM: Aksaray Eğitim ve Araştırma Hastanesine 2019-2020 yılları arasında başvuran 150 hastasının 150 gözü çalışmaya dahil edildi..28 mavi, 30 yeşil, 29 hafif kahverengi(hafif pigmentasyon), 31 orta kahverengi(orta pigmentasyon) ve 30 koyu kahverengi(ağır pigmentasyon) göz olmak üzere 5 grup hasta çalışmaya alındı. Hastalara biyomikroskobik ve fundus muayenesi yapıldı. Hastaların refraksiyonları ölçüldükten sonra, korneal topografi ve optik biyometri ile Göz İçi Basıncı(GİB), Santral Korneal Kalınlık(SKK), Ön Kamara Derinliği(ÖKD), Ön Kamara açısı(ÖKA), Lens Kalınlığı(LK), Aksiyel Uzunluk(AU) ölçümleri ve OCT ile de retinal sinir lifi kalınlığı(RSLK), santral retinal kalınlık(SRK) ve subfoveal koroid kalınlık(SFKK) ölçümleri yapıldı.
BULGULAR: Hastaların yaş ortalamaları mavi, yeşil ve kahverengi gözlü hastalarda sırası ile 33.4 ±5.5, 35.7±4,7 ve 32,9 ± 6,7 idi. Mavi gözlü grupta 15 kadın 13 erkek, yeşil gözlü grupta 16 kadın 14 erkek ve kahverengi gözlü grupta 47 erkek 43 bayan yer aldı. Ön ve arka segment parametreleri açısından mavi göz ile kahverengi göz arasında SKK, ÖKD ve LK açısından fark saptandı(p=0.035, 0.004 ve 0.012). Mavi göz ile yeşil göz arasında ÖKD ve LK açısından fark saptandı (p=0.006 ve 0.041). Yeşil göz ve kahverengi gözlü hastaların ön ve arka segment parametreleri arasında da anlamlı bir farklılık saptanmadı. Ayrıca diğer faktörler açısından da gruplar arasında fark saptanmadı. İris pigmentasyon düzeyine göre parametreler açısından yapılan korelasyon analizi sonucu hiç bir parametre ile pozitif yada negatif korelasyon saptanmadı.
TARTIŞMA: Hastalar değerlendirilirken bazı göz parametrelerinin normal değerlerinin iris rengindeki farklılıklara göre değişiklik gösterebileceği akılda bulundurulmaldır.
References
- 1. Liu, F., Wollstein, A., Hysi, P.G., et al. (2010). Digital quantification of human eye color highlights genetic association of three new loci. PLoS Genet, 6, e1000934.
- 2. Grimm, C., Wenzel. A., Williams, T., et al. (2001). Rhodopsin-mediatedblue-light damaget other at retina: effect of photoreversal of bleaching. Invest Ophthalmol Vis Sci, 42, 497–505.
- 3. Hu, D.N., Mccormick, S.A., Orlow. S.J., Rosemblat, S., Lin, A.Y., Wo, K.(1995) Melanogenesis by Human Uveal Melanocytes in-Vitro. Invest Ophtalmol Vis Sci, 36(5), 931-938
- 4. Meng, W., Butterworth, J., Calvas P., et al.(2012). Myopia and iris colour: a possible connection? Med Hypotheses, 78, 778–80.
- 5. Sun, H.P., Lin, Y., Pan, C.W. (2014). Iris color and associated pathological ocular complications: a review of epidemiologic studies. Int J Ophthalmol , 7, 872–8.
- 6. Yahalom, C., Tzur, V., Blumenfeld, A., et al. (2012). Refractive profile in oculocutaneous albinism and its correlation with final visual outcome. Br J Ophthalmol, 96, 537–9.
- 7. White, D., Rabago-Smith, M.(2011). Genotype-phenotype associations and human eye color. J Hum Genet, 56(1), 5–7.
- 8. Younan, C., Mitchell, P., Cumming, R.G., Rochtchina, E., Wang, J.J. (2002). Iris color and incident cataract and cataract surgery: the Blue Mountains Eye Study. Am J Ophthalmol, 134(2), 273–4.
- 9. Di Stasio E, Maggi D, Berardesca E, Marulli GC, Bizzarri C, Lauria A et al.(2011). Blue eyes as a risk factor for type 1 diabetes. Diabetes Metab Res Rev, 27(6),609–13.
- 10. Cumming, R.G., Mitchell, P., Lim, R. (2000) Iris color and cataract: the Blue Mountains Eye Study.Am J Ophtalmol, 130(2), 237-238
- 11. Leske, M.C, Wu, S.Y., Nemesure, B., Hennis, A.(2002). Barbadors Eye Studies Group. Risk factors for incident nuclear opacities. Ophtalmology 109(7), 1303-1308.
- 12. Schmidt-Pokrzywniak, A., Jockel, K.H., Bornfeld, N., Sauerwein, W., Stang, A.(2009). Positive Interaction Between Light Iris Color and Ultraviolet Radiation in Relation to the Risk of Uveal Melanoma A Case-Control Study, 116(2), 340-348.
- 13. Klein, R., Klein, B.E., Jensen, S.C., Cruickshanks, K.J. (1998). The relationship of ocular factors to the incidence and progression of age-related maculopathy. Arch Ophtalmol, 116(4), 506-513 .
- 14. Khan, J.C., Shahid, H., Thurlby, D.A, Bradley, M., Clayton, D.G, Moore, A.T., Bird ,A.C., Yates, J.R. (2006). Genetic Factors in AMD Study. Age related macular degeneration and sun exposure, iris colour, and skin sensitivity to sunlight. Br J Ophtalmol, 90(1), 29-32.
- 15. McCarty, C.A., Mukesh, B.N., Fu, C.L., Mitchell, P., Wang, J.J. (2001). Taylor HR. Risk factors for age-related maculopathy: the Visual Impairment Project. Arch ophtalmol, 119(10),1455-1462
- 16. Jonas, J.B., Budde, W.M., Stroux, A., Oberacher-Velten, I.M. (2006). Iris colour, optic disc dimensions, degree and progression of glaucomatous optic nerve damage, 34(7),654-660
- 17. Saw, S.M. (2003). A synopsis of the prevalence rates and environmental risk factors for myopia.Clin Exp Optom. 86(5),289-294.
- 18. Young, T.L., Metlapally, R., Shay, A.E. (2007). Complex trait genetics of refractive error. Arch Ophtalmol, 125(1), 38-48.
- 19. Vannas, A.E., Ying, G.S., Stone, R.A.,(2003). Maguire MG, Jormanainen V, Tervo T. Myopia and natural lighting extremes: risk factors in Finnish army conscripts, 81(6), 588-595.
- 20. Pan, C.W., Ke, C., Hu, D.N., Li, J., Zhong, H.(2009). Iris colour and astigmatism among Chinese teenagers. Br J Ophthalmol. 103(12), 1810-1814.
Details
| Primary Language | English |
|---|---|
| Subjects | Health Care Sciences and Services |
| Journal Section | Research Articles |
| Authors |
|
| Supporting Institution | yok |
| Project Number | yok |
| Publication Date | December 29, 2022 |
| Submission Date | October 25, 2022 |
| Acceptance Date | November 18, 2022 |
| Published in Issue | Year 2022Volume: 3 Issue: 2 |
Cite
| Bibtex | @research article { asujshr1194273, journal = {Aksaray University Journal of Sport and Health Researches}, eissn = {2757-6310}, address = {Aksaray Üniversitesi Rektörlük İdari Birimler Spor ve Sağlık Alanında İhtisaslaşma Koordinatörlüğü Aksaray/Merkez, 68100}, publisher = {Aksaray University}, year = {2022}, volume = {3}, number = {2}, pages = {168 - 176}, doi = {10.54152/asujshr.1194273}, title = {Comparison of Anterior and Posterior Segment Parameters According to Iris Color Spectrum}, key = {cite}, author = {Yaşar, Erdoğan and Gürlevik, Ugur and Bilgeç, Mustafa Değer} } |
| APA | Yaşar, E. , Gürlevik, U. & Bilgeç, M. D. (2022). Comparison of Anterior and Posterior Segment Parameters According to Iris Color Spectrum . Aksaray University Journal of Sport and Health Researches , 3 (2) , 168-176 . Retrieved from http://asujshr.aksaray.edu.tr/en/pub/issue/73325/1194273 |
| MLA | Yaşar, E. , Gürlevik, U. , Bilgeç, M. D. "Comparison of Anterior and Posterior Segment Parameters According to Iris Color Spectrum" . Aksaray University Journal of Sport and Health Researches 3 (2022 ): 168-176 <http://asujshr.aksaray.edu.tr/en/pub/issue/73325/1194273> |
| Chicago | Yaşar, E. , Gürlevik, U. , Bilgeç, M. D. "Comparison of Anterior and Posterior Segment Parameters According to Iris Color Spectrum". Aksaray University Journal of Sport and Health Researches 3 (2022 ): 168-176 |
| RIS | TY - JOUR T1 - Comparison of Anterior and Posterior Segment Parameters According to Iris Color Spectrum AU - ErdoğanYaşar, UgurGürlevik, Mustafa DeğerBilgeç Y1 - 2022 PY - 2022 N1 - DO - T2 - Aksaray University Journal of Sport and Health Researches JF - Journal JO - JOR SP - 168 EP - 176 VL - 3 IS - 2 SN - -2757-6310 M3 - UR - Y2 - 2022 ER - |
| EndNote | %0 Aksaray University Journal of Sport and Health Researches Comparison of Anterior and Posterior Segment Parameters According to Iris Color Spectrum %A Erdoğan Yaşar , Ugur Gürlevik , Mustafa Değer Bilgeç %T Comparison of Anterior and Posterior Segment Parameters According to Iris Color Spectrum %D 2022 %J Aksaray University Journal of Sport and Health Researches %P -2757-6310 %V 3 %N 2 %R %U |
| ISNAD | Yaşar, Erdoğan , Gürlevik, Ugur , Bilgeç, Mustafa Değer . "Comparison of Anterior and Posterior Segment Parameters According to Iris Color Spectrum". Aksaray University Journal of Sport and Health Researches 3 / 2 (December 2022): 168-176 . |
| AMA | Yaşar E. , Gürlevik U. , Bilgeç M. D. Comparison of Anterior and Posterior Segment Parameters According to Iris Color Spectrum. ASUJSHR. 2022; 3(2): 168-176. |
| Vancouver | Yaşar E. , Gürlevik U. , Bilgeç M. D. Comparison of Anterior and Posterior Segment Parameters According to Iris Color Spectrum. Aksaray University Journal of Sport and Health Researches. 2022; 3(2): 168-176. |
| IEEE | E. Yaşar , U. Gürlevik and M. D. Bilgeç , "Comparison of Anterior and Posterior Segment Parameters According to Iris Color Spectrum", Aksaray University Journal of Sport and Health Researches, vol. 3, no. 2, pp. 168-176, Dec. 2022, doi:10.54152/asujshr.1194273 |
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